For HTN as monotherapy or in combination with other antihypertensive agents. Heart failure (NYHA class II-IV). Reduces CV mortality in clinically stable patients with left ventricular failure or left ventricular dysfunction following MI.

This is not a substitute for consulting your doctor. Seek professional advice if you are experiencing any illness or symptoms.

Adult HTN Initially 80 or 160 mg once daily. May increase to a max of 320 mg or a diuretic may be added if additional antihypertensive effects is required. Heart failure Initially 40 mg bid. Up titration to 80 & 160 mg bid should be done to the highest dose, as tolerated by the patient. Consideration should be given to reducing the dose of concomitant diuretics. Max: 320 mg in divided doses. Post-MI Initially 20 mg bid as early as 12 hour after MI. May be given with other standard post-MI treatment , including thrombolytics, aspirin, B-Blockers, statins & diuretics. Children 6-18 year HTN Initially 1.3 mg/kg once daily (up to 40 mg total).

May be taken with or without food.