(Oral) hypercholesterolaemia, Mixed dyslipidaemia. Prophylaxis of Cardiovascular events in High-risk patients.

This is not a substitute for consulting your doctor. Seek professional advice if you are experiencing any illness or symptoms.

Adult: Dosage is individual based on treatment goals, Patient response and clinical practice guidelines. Initially, 5 or 10 mg once daily; may increased after 4 weeks if necessary. Usual Max: 20 mg once daily; a Max of 40 mg once daily may be used only in patients with severe hypecholesterolaemia at high CV risk who do not achieve the target cholesterol concentration at lower doses and who do not have risk factors for adverse effects. Patients with homozygous familial hypercholesterolaemia may be started on 20 mg once daily. dosage may be increased at intervals of 2-4 weeks. Children: Heterozygous familial hypercholesterolaemia: Initially, 5 mg once daily. Usual dose range: 6-9 years 5-10 mg once daily; 10-17 years 5-20 mg once daily, depending on age, weight and prior statin use, may titrate dose up to Max of 20 mg once daily according to individual response and tolerability, and depending on treatment recommendations. (Prophylaxis of Cardiovascular events in High-risk patients) Adult: 20 mg once daily. Elderly: >70 years Initially, 5 mg once daily. Patients of Asian ancestry; those with predisposing factors to myopathy (e.g. hypothyroidism, personal or familial history of heredity muscular disorders; alcohol abuse): Initially, 5 mg once daily. 40 mg dose is contraindicated.

may be taken with or without food.