For the treatment of gastroesophageal reflux disease, peptic ulcer disease, for eradication of Helicobacter pylori may be combined with two antibacterial in a 1-week triple therapy regimen prophylaxis for NSAID-associated ulceration and treatment of pathological hypersecretory states such as Zollinger-Ellison Syndrome.

This is not a substitute for consulting your doctor. Seek professional advice if you are experiencing any illness or symptoms.

The usual dose for the treatment of peptic ulcer disease is 40mg once daily. Treatment is usually given for 2 to 4 weeks for doudenal ulceration, or 4 to 8 weeks for benign gastric ulceration. For the eradication of Helicobacter pylori, pantoprazole may be combined with two antibacterial in a 1 week triple therapy regimen. Effective regimen include pantoprazole 40mg twice daily combined with clarithromycin 500 mg twice daily and either amoxicillin 1g twice daily or metronidazole 400mg twice daily.

In the treatment of gastroesophageal reflux the usual dose is 20 to 40 mg once daily for 4 weeks, increased to 8 weeks if necessary. For maintenance therapy, treatment can be continued with 20 to 40 mg daily.