OMEPRAZOLE
XOPRAZOLE PLUS 40MG DELAYED-RELEASE CAPSULE
40mg Delayed-Release Capsule
Indication*
Duodenal ulcer, Gastric ulcer, Nonsteroidal Anti-Inflammatory Drug (NSAID) associated gastric and duodenal ulcers or erosions Helicobacter pylori eradication in peptic ulcer disease. Reflux oesophangitis. Symptomatic gastro-oesophageal reflux disease. Treatment of erosive reflux oesophangitis, Long-term maintenance therapy to prevent reflux oesophagitis, Acid-related dyspepsia, Zollinger-Ellison syndrome, Refractory peptic ulcer, Prophylaxis of acid aspiration.
Directions for Use*
Doudenal ulcer_ Usually 20 mg once daily for 2 weeks; if not fully healed, treatment may be extended for a further 2 weeks. In refractory case, 40 mg once daily for 4 weeks. Gastric ulcer and relux oesophagitis_ 20 mg once daily for 4 weeks; if not fully healed, treatment may be extended for further 4 weeks. In refractory cases, 40 mg once daily for 8 weeks. Prevention of relapses in patients with severe reflux oesophagitis- 20 mg once daily. In case of recurrence, the dose can be increased to 40 mg once daily. Helicobacter pylori-associated peptic ulcer disease-40-80 mg with amoxicillin. 1.5 to 3g daily in divided doses for 2 weeks or 40 mg daily with clarithromycin 500 mg thrice daily for 2 weeks. Zollinger-Ellison Syndrome- 60 mg once daily adjusted to response. Usual maintenance -20 to 120mg daily. Doses over 80mg daily, can be given in two divided doses. Prophylaxis of acid aspiration-Omeprazole 40mg in the evening before surgery and 40mg 2-6 hours before surgery.
Administration*
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