Essential HTN in adults, children and adolescents 6-18yr. Renal disease in adult w/ HTN & type 2 DM w/ proteinuria≥.5g daily as part of antihypertensive treatment. Chronic heart failure in adult when treatment w/ ACE inhibitors in not considered suitable. Reduction in risk of stroke in adult hypertensive patients w/ left ventricular hypertrophy documented by ECG.

This is not a substitute for consulting your doctor. Seek professional advice if you are experiencing any illness or symptoms.

Individualized dosage. HTN Adult Usual initial & maintenance dose: 50 mg once daily, may be increased to 100 mg once daily. Patient with intravascular vol-depletion (eg, those treated with high-dose diuretics) & history of liver disease Initially 25 mg once daily. Patient with moderate to severe renal disease & those on dialysis 25mg once daily. Children >6 year weighing >50 kg 50 mg daily. Max: 100 mg daily, >20- <50 kg 25 mg daily. Max: 50 mg daily. Hypertensive patient with left ventricular hypertrophy Initially 50 mg once daily. Add hydrochlorothiazide 12.5 mg daily & or increase dose to 100 mg once daily followed by increase in hydrochlorothiazide to 25 mg once daily based on BP response. Heart failure Initially 12.5 mg once daily, titrated at weekly intervals (ie,12.5 mg daily, 25 mg daily, 50 mg daily) to usual maintenance dose of 50 mg once daily as tolerated. Nephropathy in type 2 diabetic patient Initially 50 mg once daily, may be increased to 100 mg once daily.

Maybe taken with or without food.