Indication*

Chronic Diarrhea, Acute Diarrhea.

Directions for Use*

Adult: As loperamide hydrochloride cap: Initially, 4 mg, daily; adjusted until1-2 solid stools a day are obtained, which is usually achieved with maintenance dose of 2-12 mg daily. Max: 16 mg daily. As loperamide hydrochloride oral solution: Initially, 4-8 mg daily in divided doses, may be adjusted depending on response. Doses may be given bid once the maintenance dose is established. Max: 16 mg daily. For cases associated with inflammatory bowel disease: As loperamide hydrochloride cap: Initially, 4 mg, followed by 2 mg after each loose stool until diarrhea is controlled. Usual maintenance dose: 4-8 mg daily as single dose or in divided doses. Max: 16 mg daily. If improvement does not occur after therapy with 16 mg daily for at least 10 days, symptoms are unlikely to be controlled by further use. Dosage recommendations may vary among individual products or between countries. Refer to specific product guidelines. (Acute diarrhea) Adult: As loperamide hydrochloride cap or oral solutions/suspension: Initially, 4 mg, followed by 2 mg after every subsequent loose stool. Max: 16 mg daily. As loperamide hydrochloride conventional or orodispersible tab: Initially, 4 mg, followed by 2 mg after each loose stool. Usual dose: 6-8 mg daily. Max: 12 mg daily. Discontinue treatment if clinical improvement is not observed within 48 hours. Dosage recommendations may vary among individual products or between countries. Refer to specific product guidelines. Children: As loperamide hydrochloride cap: 8-17 years Initially, 2 mg, then 2 mg after every subsequent loose stool. Max: Based om individual body weight (6 mg/20 kg) up to 16 mg daily. As loperamide hydrochloride conventional or orodispersible tab:> 12 years Same as adult dose. As loperamide hydrochloride oral solution/suspension: 6-8 years weighing 21.8-27 kg: Initially, 2 mg followed by 1 mg after every subsequent loose stool. Max: 4 mg daily; 9-11 years weighing 27.2-43 kg: Initially, 2 mg, followed by 1 mg after each loose stool. Max: 6 mg daily. Alternatively, for loperamide hydrochloride oral solution: 4-8 years 1 mg or 4 times daily for up to 3 days; >8-11 years 2 mg 4 times daily for up to 5 days. Discontinue treatment if clinical improvement is not observed within 48 hours. Dosage recommendations may vary among individual products or between countries. Refer to specific product guidelines.

Administration*

May be taken with or without food.

*written indications, directions, and administration are updated as of March 23, 2024 and may not be accurate with the actual product purchased. Please read the details in the packaging.