Prophyalaxis treatment of angina pectoris.

This is not a substitute for consulting your doctor. Seek professional advice if you are experiencing any illness or symptoms.

60 mg once daily to be taken in the morning. The dose may be increased to 120 mg daily, taken once daily in the morning. The dose can be titrated to minimize the possibility of headache by initiating treatment with 30 mg for the first 2-4 days. The tablets can be taken with or without food. The 30 mg and 60 mg tablets are scored and dividable. The whole tablets or if needed or if needed the divided halves, should not be chewed or crushed and should be swallowed together with half a glass of fluid. Isosorbide-5-mononitrate (IMDUR DURULES) is not indicated for the relief of acute attacks. In these situations sublingual or buccal nitroglycerine tablets or spray formulations should be used. The matrix of the tablet is insoluble but disintegrates when the active substance is released. Occasionally the matrix may pass through the gastrointestinal tract without disintegrating and may be visible in the stool but this dose not indicate that the drug has had a reduced effect.

Shall be taken with or without food: May be divided along score-line> Whole tabs & divided halves must be swallowed whole. do not chew/crush.