Indication*

Enalapril is an ACE inhibitor used in the treatment of hypertension and heart failure. It may also be given prophylactically to patients with asymptomatic left ventricular dysfunction to delay the onset of symptomatic heart failure and to those with left ventricular dysfunction to reduce the incidence of coronary ischaemic events including myocardial infraction.

Directions for Use*

HTN Initially 5mg/day. Usually 10-40 mg/day as a single or 2 divided doses. Renal impairment CrCI <30 mL/min (serum creatine >3mg/dL) 2.5mg once daily on the 1st dose. Then may titrate dose upward until BP is controlled. Max: >0.58 mg/kg (or >40mg). Heart failure Initially 2.5 mg/day. Maintenance: 20 mg/day as a single dose or in 2 divided doses. Asymptomatic left ventricular dysfunction Initially, 2.5mg bid. Titrate as tolerated to the targeted daily dose of 20 mg in divided doses. Renal impairment (serum creatinine >1.6 mg/dL) or hyponatremia (serum Na <130 mEq/L) Initially at 2.5 mg daily. May increase dose to 2.5 bid, then 5mg bid & higher as needed, usually at intervals of 4 days or more. Max daily dose: 40mg.

Administration*

Initial Dose: Usual is 5 mg by mouth. 2.5 mg in patients with renal impairment or on diuretic; and in the elderly. Maintenance Dose: 10 mg to 20 mg, once daily. Heart Failure: Initial dose is 2.5 mg daily and slowly increased up to 20 mg daily as tolerated. Or as prescribed by the physician.

*written indications, directions, and administration are updated as of January 28, 2024 and may not be accurate with the actual product purchased. Please read the details in the packaging.

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