EMPAGLIFLOZIN + METFORMIN HCL
JARDIANCE DUO 12.5MG/500MG TABLET
12.5mg/500mg Tablet
Indication*
Adjunct to diet & exercise to improve glycemic control in adults with type 2 DM when treatment with both empagliflozin & metformin is appropriate. Adults with type 2 DM & established CV disease to reduce the risk of CV death; should be used in conjunction with other measures to reduce CV risk in line with the current standard care.
Directions for Use*
Recommended dose: 1 tab bid. Adult with normal renal function (GFR >90 ml/min) Max daily dose: 25mg/2,000 mg. Patient not adequately controlled on metformin alone or in combination with other products including insulin Empagliflozin 5mg bid+ metformin dose already being taken. Patients tolerating a total daily dose of empagliflozin 10mg May be increased to empagliflozin 25mg total daily dose. Patients already treated with empagliflozin Continue to take the same empagliflozin daily dose. Patient switching from separate tab of empagliflozin & metformin already being taken or the nearest therapeutically appropriate dose of metformin. Renal impairment eGFR 60-89 mL/min Max daily dose: 3,000 mg for metformin, 25 mg for empagliflozin; 45-59 mL/min Max daily dose: 2,000 mg for metformin, no dose adjustment required for empagliflozin; 30-44 mL/min Max daily dose: 1,000 mg for metformin, no dose adjustment required for empagliflozin.
Administration*
Should be taken with food: Take with meals to reduce GI discomfort.
*written indications, directions, and administration are updated as of June 08, 2024 and may not be accurate with the actual product purchased. Please read the details in the packaging.
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