Management of peripheral vascular disease.

This is not a substitute for consulting your doctor. Seek professional advice if you are experiencing any illness or symptoms.

Intermittent Claudication, Adult: In patients without rest pain or peripheral tissue necrosis; as second-line patients for whom lifestyle modifications and drugs treatment or interventions are sufficient: 100 mg bid. Reassess therapy after 3 months. Patient taking strong or moderate inhibitors of CYP3A4 or CYP2C19 (e.g. certain macrolides, azole antifungals, protease inhibitors, proton pump inhibitors): 50 mg bid.

Should be taken on an empty stomach: Take at least 30 min before or 2 hr after breakfast or dinner.