ATORVASTATIN CALCIUM
LIPITOR 40MG FILM-COATED TABLET
40mg Film-coated Tablet
Indication*
Adjunct to diet for the treatment of patients with elevated total cholesterol (total-C), LDL-C, Apo B, & Triglycerides (TG) & to increase HDL-C in patients with primary hypercholesterolemia (heterozygous familial & Nonfamilial hypercholesterolemia), combined (mixed) hyperlipidemia (Fredrickson types IIa & IIb), elevated serum TG levels (Fredrickson type IV), & for patients with dysbetalipoproteinemia (Fredrickson type III) who dot respond adequately to diet. Reduction of total-C & LDL-C in patients with HoFH. Reduce the risk of fatal CHD & non-fatal MI, stroke, revascularization procedures & angina pectoris in patients without clinically evident CV disease, & with or without dyslipidemia, but with multiple risk factors for CHD (eg, smoking, HTN, diabetes, low HDL-C, or a family history of early CHD). Reduce the risk of non-fatal MI, fatal & non-fatal stroke, revascularization procedures, hospitalization for CHF, & angina in patients with clinically evident CHD. Adjunct to lifestyle changes (eg, proper diet & exercise) to halt the progression of atherosclerosis (total atheroma of plaque vol) in patients with CAD & other individuals who are at high risk for CV disease. Reduce the risk for CV disease in patients with diabetes with moderately decreased eGFR. Reduce the risk rate of major GFR decline & progression of CKD in patients with clinically evident CHD & CKD not requiring dialysis. Reduce the risk of major CV events including stroke in patients with clinically evident CHD &/or diabetes with microalbuminuria. Adjunct to diet to reduce total-C & Apo B levels in boys & post-menarchal girls 10-17 year with heterozygous familial hypercholesterolemia if after an adequate trial of diet therapy the LDL-C remains >190 mg/dL or LDL-C remains >160 mg/dL, & there is a +ve family history of premature CVD or >2 other CVD risk factors are present.
Directions for Use*
Individualized starting & maintenance dose. Dose range: 10-80 mg once daily . Primary hypercholesterolemia & combined (Mixed) hyperlipidemia 10 mg once daily. HoFH 80 mg. Co-administration with cyclosporine, telaprevir, tipranavir/ritonavir, or glecaprevir/pibrentasvir Max: 10 mg. Severe dyslipidemia Children> 10 year 10 mg once daily, may be increased to 80 mg daily. Adjustment should be made at >4 week intervals.
Administration*
May be taken with or without food.
*written indications, directions, and administration are updated as of March 23, 2024 and may not be accurate with the actual product purchased. Please read the details in the packaging.
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