Asthma: Budesonide+ Formoterol fumarate dihydrate (Symbicort Rapihaler) is indicated in the regular treatment of asthma where use of a combination (inhaled corticosteroid and long-acting beta2-agonist) is appropriate. COPD: Budesonide + Formoterol dihydrate (Symbicort Rapihaler) is indicated in the regular treatment of patients with moderate to severe chronic obstructive pulmonary disease (COPD), with frequent symptoms and a history of exacerbations.

This is not a substitute for consulting your doctor. Seek professional advice if you are experiencing any illness or symptoms.

The patients should be instructed that Budesonide + Formoterol fumarate dihydrate (Symbicort Rapihaler) must be used even when asymptomatic for optimal benefit. There are no special dosing requirements for elderly patients. There are no date available for use of Budesinide + Formoterol fumarate dihydrate (Symbicort Rapihaler) in patients with hepatic or renal impairment. As budesonide and formoterol are primarily eliminated via hepatic metabolism, an increased exposure can be expected in patients with severe liver diseases. *Instructions for correct use of Budesonide + Formoterol fumarate dihydrate (Symbicort Rapihaler): On actuation of Budesonide + Formoterol fumarate dihydrate (Symbicort Rapihaler), a volume of the suspension is expelled from the canister at high velocity. When the patient inhales through the mouthpiece at the same time as actuating the inhaler, the substance will follow the inspired air into the airways. Note: It is important to instruct the patient to: Carefully read the instructions for use, handling and disposal under Cautions for Usage. Shake the inhaler gently prior to each use to mix its contents properly. Prime the inhaler by actuating it twice into the air when the inhaler is new, has not been used for more than one week or if it has been dropped. Place the mouthpiece in the mouth. While breathe in and hold the breath for approximately 10 seconds or as long as in comfortable. Shake the inhaler again and repeat. Rinse the mouth with water after inhaling the maintenance dose to minimise the risk of oropharyngeal; thrush. Clean the mouthpiece of the inhaler regularly, at least once a week with a clean dry cloth. Do not put the inhaler into water.